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    Aliases: wellbutrin, zyban, amfebutamone

    Summary

    A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.

    Onset, Duration & After-effects

    • Onset:
      • 15-90 minutes
    • Duration:
      • Metabolites: 20-37 hours
      • Parent: 11-21 hours
    • After-effects:
      • 1-6 hours

    Helpful Links

    Known Combinations

    No interaction data available from Tripsit

    Studies & References

    • Evaluation of a Potential Metabolism-Mediated Drug-Drug Interaction Between Atomoxetine and Bupropion in Healthy Volunteers. http://www.ncbi.nlm.nih.gov/pubmed/27518170