These combinations are considered extremely harmful and should always be avoided.
alcohol
amt
ghb/gbl
maois
mdma
mephedrone
opioids
pcp
ssris
tramadol
Dextromethorphan
Aliases: dxm, robo, syrup, robotussin, dex, robitussin
Categories
Summary
Commonly found in certain over the counter cough medicines. Has dissociative effects similar to ketamine or MXE, though also shares properties with opioids and alcohol. Make sure DXM is the only active ingredient in the preparation.
Dose Information
Onset, Duration & After-effects
- Onset:
- 20-60 minutes
- Duration:
- 6-8 hours
- After-effects:
- 1-12 hours
Helpful Links
Known Combinations
Studies & References
- Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors.
- Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squirrel monkeys.
- Dextromethorphan psychosis, dependence and physical withdrawal.
- Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice.
- Dextromethorphan as a potential rapid-acting antidepressant.
- The treatment of heroin addicts with dextromethorphan: a double-blind comparison of dextromethorphan with chlorpromazine.
- High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens.
- Lack of efficacy of dextromethorphan in managing alcohol withdrawal: a preliminary report of a randomized, double-blind, placebo-controlled trial.