Diazepam
Aliases: valium
Categories
Summary
A very common and widely prescribed benzodiazepine with hypnotic and sedative qualities. The metre by which other benzodiazepines are compared. May cause amnesia and lowered inhibitions in excess. Has a relatively long half-life in comparison with other benzodiazepines.
Dose Information
Onset, Duration & After-effects
- Onset:
- 30-90 minutes
- Duration:
- 10-24 hours
- After-effects:
- 1-120 hours
Effects
- Memory loss
- Blackout potential
- Motor skill impairment
- Dizziness
- Depression
- Irritability
- Aggression
- Rage
- Personality changes
- Drowsiness
- Appetite fluctuation
- Euphoria
- Relaxation
- Anxiety suppression
- Muscle relaxation
- Emotional and social dissociation or de-realization (normally seen with long term use)
Helpful Links
Known Combinations
Studies & References
- Alcohol and benzodiazepines in fatal poisonings.
- NMDA receptor antagonists potently suppress the spontaneous withdrawal signs induced by discontinuation of long-term diazepam treatment in Fischer ...
- Dual intoxication with diazepam and amphetamine: this drug interaction probably potentiates myocardial ischemia.
- Effect of omeprazole and cimetidine on plasma diazepam levels.
- Bioavailability of intranasal vs. rectal diazepam.
- Dosing feasibility and tolerability of intranasal diazepam in adults with epilepsy.