Heroin
Aliases: diamorphine
Categories
Summary
A powerful opioid derived from Morphine, with 2-4x its potency. Infamous for a high addiction potential and fatal respiratory depression in overdose, C. R. Alder Wright first synthesised this compound in 1874 trying to find a less addictive alternative to Morphine. In recent years, it has often been sold cut with the extremely potent fentanyl, causing a spike in overdose deaths.
Dose Information
Onset, Duration & After-effects
- Onset:
- Smoked: 5-10 minutes
- Insufflated: 10-15 minutes
- Intravenous: 0-5 minutes
- Duration:
- Insufflated: 3-6 hours
- Intravenous: 4-5 hours
- Smoked: 3-5 hours
- After-effects:
- 1-24 hours
Effects
- Euphoria
- Dry Mouth
- Mood lift
- Itchiness
- Relaxant
- Constipation
- Pupil Constriction
- Analgesia
Helpful Links
Known Combinations
Studies & References
- Disrupted white matter integrity in heroin dependence: a controlled study utilizing diffusion tensor imaging
- The treatment of heroin addicts with dextromethorphan: a double-blind comparison of dextromethorphan with chlorpromazine
- Effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) and quipazine on heroin self-administration in rhesus monkeys
- Heroin "overdose" death: contribution of drug-associated environmental cues
- Methadone trials have proven successful in treating Heroin addiction
- Heroin has been linked to reduction in testosterone and DHT levels