These combinations are considered extremely harmful and should always be avoided.
amt
dextromethorphan
lithium
maois
mephedrone
tramadol
MDMA
Aliases: molly, ecstasy, adam, xtc, mandy, x, md
Categories
Summary
The world's most popular empathogen with powerful pro-social effects. Has been strongly linked to cognitive decline in excess. Popular at parties, it is often sold in powder or in pills, and may be adulterated with other similar chemicals.
Dose Information
Onset, Duration & After-effects
- Onset:
- 20-70 minutes
- Duration:
- 3-5 hours
- After-effects:
- 1-72 hours
Helpful Links
Known Combinations
Studies & References
- Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity
- Involvement of free radicals in MDMA-induced neurotoxicity in mice.
- Methamphetamine and MDMA (ecstasy) neurotoxicity: 'of mice and men'.
- The neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine on serotonin, dopamine, and GABA-ergic terminals
- MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment.
- Pharmacological aspects of the combined use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and gamma-hydroxybutyric acid (GHB)
- 3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings.
- The effects of fluoxetine on the subjective and physiological effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans
- Neurogenic bladder and chronic urinary retention associated with MDMA abuse.
- THC Prevents MDMA Neurotoxicity in Mice
- Effects of a beta-blocker on the cardiovascular response to MDMA (Ecstasy).
- Neurotoxicity of ecstasy (MDMA): an overview
- MDMA: interactions with other psychoactive drugs
- MDMA and temperature: a review of the thermal effects of 'Ecstasy' in humans.
- MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral...
- MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase.
- MDMA Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner.
- Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: implications for the pathogenesis of free radical
- MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons.
- MDMA, cortisol, and heightened stress in recreational ecstasy users.
- A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds.
- Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum.
- MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac).
- Ecstasy use and serotonin syndrome: a neglected danger to adolescents and young adults prescribed selective serotonin reuptake inhibitors.
- 3,4-Methylenedioxymethamphetamine (ecstasy) and alcohol interactions in humans: psychomotor performance, subjective effects, and pharmacokinetics.
- Putting an Ecstasy test kit to the test: harm reduction or harm induction?
- MDMA Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing population.
- Monoamine oxidase-B mediates ecstasy-induced neurotoxic effects to adolescent rat brain mitochondria.
- Increased oxytocin concentrations and prosocial feelings in humans after ecstasy (3,4-methylenedioxymethamphetamine) administration.
- Neurotoxicity of ecstasy (MDMA): an overview.
- Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats
- Neurotoxicity of ecstasy and its metabolites in human dopaminergic differentiated SH-SY5Y cells.
- Neuroprotective properties of melissa officinalis L. Extract against ecstasy-induced neurotoxicity.
- Ecstasy use and serotonin syndrome: a neglected danger to adolescents and young adults prescribed selective serotonin reuptake inhibitors.
- MDMA, cortisol, and heightened stress in recreational ecstasy users
- History of MDMA
- Study associating long-term serotonergic injury from use of MDMA
- Even after abstaining as long as 2.5 years, verbal memory deficits were still present in ex-mdma abuserd, indicating that the neurotoxicity may have some permanent damage features
- http://onlinelibrary.wiley.com/doi/10.1002/nrc.20023/abstract Potentiation of (DL)-3,4-methylenedioxymethamphetamine (MDMA)-induced toxicity by the serotonin 2A receptior partial agonist d-lysergic acid diethylamide (LSD), and the protection of same by the serotonin 2A/2C receptor antagonist MDL 11,939