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    Aliases: tram

    Summary

    A synthetic opioid analgesic, tramadol is used to treat moderate pain and can be considered a medium-strength opioid. Tramadol also has the unusual effect of being a serotonin releasing agent and a serotonin reuptake inhibitor, and as a consequence should not be taken in excess due to the risk of serotonin syndrome. Risk of seizures above 300mg doses.

    ⚠️ AVOID: benzos, alcohol, and other opiates
    ⚠️ Tramadol has a ceiling dose, where recreational effects are not increased. Risk of seizure at doses over 300mg. Tramadol decreases the seizure threshold, use extreme caution. Dosing insufflated is ineffective.

    Dose Information

    Onset, Duration & After-effects

    • Onset:
      • 1 hours
    • Duration:
      • 5-7 hours
    • After-effects:
      • 1-12 hours

    Effects

    • euphoria
    • elevated mood
    • overall feeling of contentedness
    • itching
    • drowsiness
    • vomiting
    • urinary retention
    • nausea
    • constipation
    • risk of seizure above 300mg

    Helpful Links

    Known Combinations

    These combinations are considered extremely harmful and should always be avoided.

    alcohol
    amphetamines
    amt
    benzodiazepines
    cocaine
    dextromethorphan
    ghb/gbl
    ketamine
    lithium
    maois
    mdma
    mxe
    opioids
    pcp
    ssris

    Studies & References